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    Your first drink of the night,engineered.

    The world's first genetically engineered probiotic.Designed to break down acetaldehyde, a byproduct of alcohol.

Gluten free

Nut free

Dairy free

Sugar free

Shellfish/Fish free

Vegan friendly

Gluten free

Nut free

Dairy free

Sugar free

Shellfish/Fish free

Vegan friendly

The Science

The world’s first genetically engineered probiotics: purpose-built to improve daily life.

We start with a natural probiotic bacteria you already eat every day, called Bacillus subtilis. We then used a process naturally honed by bacteria to insert the instructions for making ALDH into the bacteria’s genome...

Fiber plays an important role in our health but most of us aren’t getting enough fiber in our modern diets. We need 25-30 grams of fiber per day but about 95% of us don’t meet that goal...

It's not magic,It's science

 

Alcohol produces acetaldehyde

When we drink, our bodies break down alcohol into an unwanted byproduct called acetaldehyde.

That byproduct is largely responsible for how we feel the day after drinking.

Acetaldehyde builds up in the gut

Acetaldehyde forms in two places: the liver and the gut.

The liver produces an enzyme that removes it quickly. But the gut does not. So acetaldehyde builds up and lingers, filtering out into the rest of our body over time.

Pre-Alcohol breaks it down

Pre-Alcohol helps our gut catch up by temporarily adding a probiotic that can break down acetaldehyde.

This probiotic – Bacillus subtilis ZB183™ – has been engineered to produce the same type of enzyme as our liver: one that digests acetaldehyde.

Proudly built with genetic engineering

The ZBiotics team invented the probiotic in Pre-Alcohol – Bacillus subtilis ZB183™ – using genetic engineering.

Our approach to biotechnology is safety-first and grounded in the strictest ethical principles. We build responsibly or we don’t build at all. Pre-Alcohol undergoes rigorous quality testing at every stage, and we transparently publish our findings on our Quality page which can be found here.

How It Works

The Problem

When you drink alcohol, an unwanted byproduct called acetaldehyde forms in your gut, creating particularly rough feelings for you the next morning.

The Solution

ZBiotics® Pre-Alcohol Probiotic Drink is the only product that breaks down acetaldehyde while you drink, helping you feel better the morning after.

 

Other products are different mixes of the same 5+ off-the-shelf vitamins and plant extracts.

We took a different approach.

Using biotechnology, we identified a major unwanted byproduct of drinking alcohol—acetaldehyde—and engineered a probiotic to break it down the same way your liver does.

World's first genetically engineered probiotic

  • Trusted by customers
  • GRAS & FDA safety compliant
  • Responsibly engineered
  • Transparently labeled
  • 1 Drink Pre-Alcohol

    Make it your first drink of the night.

  • 2 Drink responsibly

    Pace yourself, hydrate, and get a good night’s sleep.

  • 3 Enjoy tomorrow

    Wake up refreshed.

    • Social events

      Enjoy the night and be ready for Sunday brunch, a workout, or family time.

    • Business outings

      Make the most of your 5-9 without worrying about your 9-5.

    • Vacation and travel

      Savor the drinks, soak in every moment, and wake up ready for your next adventure.

      Modern genetic engineering, done responsibly


      Innovation should be responsible, transparent, and trustworthy. That’s why we spent years developing the world’s first genetically engineered probiotic with rigorous testing and scientific integrity. Since launching in 2019, we’ve earned the confidence of thousands by delivering real, research-backed results.

      • When do I take it?

        The earlier, the better—ideally before your first drink. But any time before or during drinking can still help.

      • How long does it last?

        The probiotic stays active for 18-24 hours, covering you for the whole day.

      • How does it taste?

        It’s slightly tart, like lemon water, with minimal aftertaste.

      • What is acetaldehyde?

        A byproduct of alcohol metabolism linked to next-day misery. Pre-Alcohol helps break it down in your gut.

      • How should I store it?

        Keep at room temperature with the cap on. No refrigeration needed.

      • Why is ZBiotics better?

        It’s the only patented, genetically engineered probiotic designed to break down acetaldehyde—unlike other products using generic vitamins and extracts.

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